Argentine Franco Colapinto will drive for Alpine for the next five grands prix, replacing Jack Doohan.
The team said in a statement that Colapinto, whom Alpine signed from Williams over the winter, would drive alongside Pierre Gasly from the Emilia-Romagna Grand Prix at Imola on 16-18 May.
There will then be a "new evaluation before the British Grand Prix", which is on 4-6 July.
Doohan has driven for Alpine since last year's season-ending Abu Dhabi Grand Prix and has yet to score a point.